Home Introduction Prefaces Introduction to the classification How to Use This Classification Subcommittees and working groups The Classification Table of contents Part I: The primary headaches Part II: The secondary headaches Part III: Cranial neuralgias, facial pain and other headaches Appendix Definition of Terms

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5. HEADACHE ATTRIBUTED TO HEAD AND/OR NECK TRAUMA 6. HEADACHE ATTRIBUTED TO CRANIAL OR CERVICAL VASCULAR DISORDER 7. HEADACHE ATTRIBUTED TO NON-VASCULAR INTRACRANIAL DISORDER 8. HEADACHE ATTRIBUTED TO A SUBSTANCE OR ITS WITHDRAWAL 8.1. Headache induced by acute substance use or exposure  8.1.1. Nitric oxide (NO) donor-induced headache [X44]8.1.1.1. Immediate NO donor-induced headache [X44] 8.1.1.2. Delayed NO donor-induced headache [X44] 8.1.2. Phosphodiesterase (PDE) inhibitor-induced headache [X44] 8.1.3. Carbon monoxide-induced headache [X47] 8.1.4. Alcohol-induced headache [F10]8.1.4.1. Immediate alcohol-induced headache [F10] 8.1.4.2. Delayed alcohol-induced headache [F10] 8.1.5. Headache induced by food components and additives 8.1.5.1. Monosodium glutamate-induced headache [X44] 8.1.6. Cocaine-induced headache [F14] 8.1.7. Cannabis-induced headache [F12] 8.1.8. Histamine-induced headache [X44] 8.1.8.1. Immediate histamine-induced headache [X44] 8.1.8.2. Delayed histamine-induced headache [X44] 8.1.9. Calcitonin gene-related peptide (CGRP)-induced headache [X44] 8.1.9.1. Immediate CGRP-induced headache [X44] 8.1.9.2. Delayed CGRP-induced headache  [X44] 8.1.10. Headache as an acute adverse event attributed to medication used for other indications [code to specify substance] 8.1.11. Headache attributed to other acute substance use or exposure [code to specify substance] 8.2. Medication-overuse headache (MOH) 8.3. Headache as an adverse event attributed to chronic medication [code to specify substance] 8.4. Headache attributed to substance withdrawal Bibliography9. HEADACHE ATTRIBUTED TO INFECTION 10. HEADACHE ATTRIBUTED TO DISORDER OF HOMOEOSTASIS 11. HEADACHE OR FACIAL PAIN ATTRIBUTED TO DISORDER OF CRANIUM, NECK, EYES, EARS, NOSE, SINUSES, TEETH, MOUTH OR OTHER FACIAL OR CRANIAL STRUCTURES 12. HEADACHE ATTRIBUTED TO PSYCHIATRIC DISORDER 

IHS	Diagnosis	ICD-10
8.1.8	Histamine-induced headache [X44]	G44.40

Comment:

Histamine has been shown to cause an immediate headache in non-headache sufferers and an immediate as well as a delayed headache in migraine sufferers. The latter fulfils criteria for 1.1 Migraine without aura. The headache-inducing property of histamine has been studied after intravenous administration, after cutaneous administration and after inhalation: all routes of administration have the same effect. The mechanism is primarily mediated via the H1 receptor because it is almost completely blocked by mepyramine.

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IHS vs. ICD-10

To facilitate headache diagnosis in daily practice, the classification provides the corresponding WHO ICD-10NA codes for each IHS code.

IHS Subcommittee

The Classification Subcommittee prepares and revises the International Classification of Headache Disorders.

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Cephalalgia

Cephalalgia is the official journal of the IHS. It contains original papers on all aspects of headache. The journal provides an international forum for original research papers, review articles and short communications.www.cephalalgia.org

IHS Discussion Group

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